Juleen Zierath, Professor and Scientific Director, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen; and Karolinska Institutet, Stockholm, Sweden
Epigenetic Control and the Circadian Clock: Turning Back Time on Diabetes Pathogenesis
Physical activity has a documented positive effect in preventing and treating type 2 diabetes. But does it make a difference when we exercise? This is one question international collaboration will address by examining the extent to which and how the body’s circadian rhythm influences the ability of muscles to take up and metabolize sugar from the blood and the effects of exercise in relation to type 2 diabetes. The project will map the body’s biological clock, which controls the body’s circadian rhythm, to develop innovative physical activity and dietary strategies to improve prevention and treatment of type 2 diabetes.