Grant recipient
Kresten Lindorff-Larsen, Professor, Department of Biology, University of Copenhagen, Denmark

Project title
PRISM: Protein Interactions and Stability in Medicine and Genomics

Co-applicants
Torben Hansen, Professor, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark

Michele Vendruscolo, Professor, Department of Chemistry, University of Cambridge, United Kingdom

Douglas M. Fowler, Associate Professor, Department of Genome Sciences, University of Washington, Seattle, USA

Brief description
The researchers will integrate computer-based biophysics, high-throughput protein chemistry and genome analysis to understand how changes in the genome affect protein biology and how this knowledge can be used to diagnose and ultimately treat people with diseases.