This project will use new strategies to develop specific antibiotics to combat the serious and growing threat to health arising from infections caused by multidrug-resistant bacteria. Specifically, the project will exploit and explore the ability of peptides to permeate the cell walls and cell membranes of bacteria, because these peptides may facilitate the development of genetically targeted antibiotics.
“Our vision is to establish a knowledge and technology platform for developing new antibiotics that will keep pace with the development of antibiotic resistance, thereby complementing and reinforcing the use of existing antibiotics,” says Peter Eigil Nielsen.
Peter Eigil Nielsen, Professor, Department of Cellular and Molecular Medicine, University of Copenhagen
Anders Løbner-Olesen, Professor, Section for Functional Genomics, Department of Biology, University of Copenhagen
Anette Hammerum, Senior Researcher, Statens Serum Institut, Copenhagen
Henrik Franzyk, Associate Professor, Section for Natural Products and Peptides, Department of Drug Design and Pharmacology, University of Copenhagen