Saturday, 22 December 2018

Grant recipient
Torben Heick Jensen, Professor, Department of Molecular Biology and Genetics, Aarhus University, Denmark
Project title
Function, Structure, Regulation and Targeting of Exosome Adapter Complexes
Co-applicants
Elena Conti, Honorary Professor, Ludwig Maximilian University of Munich and Director, Max Planck Institute of Biochemistry, Martinsried, Germany
Jens S. Andersen, Professor, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense
Brief description
Our genetic material, the genome, produces RNA that forms either proteins or independent RNA molecules. However, genomic DNA is hyperactive, and only a fraction of the RNA produced ends up being functional molecules. The rest degrade. Which molecular machines detect and remove inappropriate RNA so that the cells do not drown in their own molecular waste? This is the question that the Exo-Adapt research centre will focus on for the next 6 years.